All lanes of I-26E have reopened following an accident that closed the two left-hand lanes around 1 p.m.
The crash happened near the Ashley Phosphate Road exit, mile marker 209.
The Highway Patrol reported injuries in the crash, but no further information was immediately available.
Crews worked to remove the vehicles involved to the side of the road to get traffic moving.
Traffic was sluggish in the area immediately after all lanes reopened.