Quantcast

FDA OKs 1st drug to treat smallpox, in case of terror attack - Live5News.com | Charleston, SC | News, Weather, Sports

FDA OKs 1st drug to treat smallpox, in case of terror attack

(Fred Murphy/CDC via AP). This 1975 microscope image made available by the Centers for Disease Control and Prevention shows a cluster of smallpox viruses. On Friday, July 13, 2018, U.S. regulators announced the approval of the first treatment for small... (Fred Murphy/CDC via AP). This 1975 microscope image made available by the Centers for Disease Control and Prevention shows a cluster of smallpox viruses. On Friday, July 13, 2018, U.S. regulators announced the approval of the first treatment for small...
(SIGA via AP). This undated photo provided by SIGA in July 2018 shows capsules of the drug TPOXX. On Friday, July 13, 2018, U.S. regulators announced the approval of the first treatment for smallpox _ a deadly disease that was wiped out four decades ag... (SIGA via AP). This undated photo provided by SIGA in July 2018 shows capsules of the drug TPOXX. On Friday, July 13, 2018, U.S. regulators announced the approval of the first treatment for smallpox _ a deadly disease that was wiped out four decades ag...

By LINDA A. JOHNSON
AP Medical Writer

U.S. regulators Friday approved the first treatment for smallpox - a deadly disease that was wiped out four decades ago - in case the virus is used in a terror attack.

Smallpox, which is highly contagious, was eradicated worldwide by 1980 after a huge vaccination campaign.

But people born since then haven't been vaccinated, and small samples of the smallpox virus were saved for research purposes, leaving the possibility it could be used as a biological weapon.

Maker SIGA Technologies of New York has already delivered 2 million treatments that will be stockpiled by the government, which partially paid for the development of the drug, called TPOXX.

To test the drug's effectiveness, monkeys and rabbits were infected with a similar virus and then given the drug. More than 90 percent survived, the company said. Its safety was tested in several hundred healthy volunteers, who were not infected with smallpox.

Smallpox killed about 300 million people worldwide in the 20th century before its eradication. Symptoms include fever, fatigue and pus-filled sores. Until now, doctors could only provide supportive care such as IV fluids and fever remedies and isolate the patients. Vaccination can be used to prevent infection but it must be done within five days of exposure to the virus, well before symptoms appear.

"This new treatment affords us an additional option should smallpox ever be used as a bioweapon," Dr. Scott Gottlieb, head of the Food and Drug Administration, said in a statement.

The drug is a capsule, taken twice daily for 14 days.

SIGA develops vaccines and medicines for biological, chemical, radiological and nuclear attacks. Chief Executive Phil Gomez said the company is developing an IV version and is exploring selling the drug to other countries and developing it to treat other infectious diseases, including monkeypox, which African monkeys can transmit to humans. Monkeypox can then spread among people, and has a mortality rate of about 15 percent.

___

Follow Linda A. Johnson at https://twitter.com/LindaJ_onPharma

___

The Associated Press Health & Science Department receives support from the Howard Hughes Medical Institute's Department of Science Education. The AP is solely responsible for all content.

Copyright 2018 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

  • NationalMore>>

  • Jupiter's moon count reaches 79, including tiny 'oddball'

    Jupiter's moon count reaches 79, including tiny 'oddball'

    Tuesday, July 17 2018 10:10 AM EDT2018-07-17 14:10:00 GMT
    Tuesday, July 17 2018 11:26 AM EDT2018-07-17 15:26:46 GMT
    (GSFC) via AP, File). FILE - This April 3, 2017 image made available by NASA shows the planet Jupiter.   A team of astronomers is reporting the recent discovery of a dozen new moons circling the giant gas planet. That brings the number of moons at Jupi...(GSFC) via AP, File). FILE - This April 3, 2017 image made available by NASA shows the planet Jupiter. A team of astronomers is reporting the recent discovery of a dozen new moons circling the giant gas planet. That brings the number of moons at Jupi...
    Scientists have found more moons circling Jupiter, bringing the total to 79 at the giant gas planet.More >>
    Scientists have found more moons circling Jupiter, bringing the total to 79 at the giant gas planet.More >>
  • Charlottesville parks aren't ready for Justice, Emancipation

    Charlottesville parks aren't ready for Justice, Emancipation

    Tuesday, July 17 2018 7:22 AM EDT2018-07-17 11:22:02 GMT
    Tuesday, July 17 2018 11:24 AM EDT2018-07-17 15:24:47 GMT
    (Zack Wajsgras/The Daily Progress via AP, File). FILE - In this Feb. 27, 2018, file photo, Jason Kessler walks through a crowd of protesters in front of the Charlottesville Circuit Courthouse ahead of a decision regarding the covered Confederate statue...(Zack Wajsgras/The Daily Progress via AP, File). FILE - In this Feb. 27, 2018, file photo, Jason Kessler walks through a crowd of protesters in front of the Charlottesville Circuit Courthouse ahead of a decision regarding the covered Confederate statue...
    Charlottesville's leaders have decided their city isn't ready for Emancipation and Justice, giving the former Lee and Jackson parks neutral names.More >>
    Charlottesville's leaders have decided their city isn't ready for Emancipation and Justice, giving the former Lee and Jackson parks neutral names.More >>
  • Washington Metro workers approve strike amid rising tensions

    Washington Metro workers approve strike amid rising tensions

    Monday, July 16 2018 9:58 AM EDT2018-07-16 13:58:10 GMT
    Tuesday, July 17 2018 11:14 AM EDT2018-07-17 15:14:07 GMT
    After years without a new contract, the Washington Metro's largest union has overwhelmingly authorized a strike, just as thousands of tourists arrive in the nation's capital for this week's Major League Baseball...More >>
    After years without a new contract, the Washington Metro's largest union has overwhelmingly authorized a strike, just as thousands of tourists arrive in the nation's capital for this week's Major League Baseball All-Star Game.More >>
Powered by Frankly